Regulatory Status
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Safety Data
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Expert Verdict
Pharmaceutical-grade MMP inhibitor with no cosmetic toxicological monograph; systemic effects at pharmacological doses include wound healing impairment and would require a full novel-ingredient safety dossier under EU Regulation 1223/2009 before cosmetic use.
Frequently Asked Questions
Is Ilomastat safe in cosmetics?
Pharmaceutical-grade MMP inhibitor with no cosmetic toxicological monograph; systemic effects at pharmacological doses include wound healing impairment and would require a full novel-ingredient safety dossier under EU Regulation 1223/2009 before cosmetic use. The EU classifies Ilomastat as "permitted". Safety rating: POOR.
Is Ilomastat allowed in the EU?
Ilomastat EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ilomastat do in cosmetics?
Ilomastat functions as: Broad-spectrum MMP (matrix metalloproteinase) inhibitor; anti-aging research active. It is classified as a cosmetic ingredient in our database. CAS number: 142880-36-2 [^1_14][^1_15].
What is the Margin of Safety for Ilomastat?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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