Indolebutyroyl Aspartic Acid

INCI: INDOLEBUTYROYL ASPARTIC ACID

CAS Number
101289-65-0 ; alternate listing 73211-20-8 — confirm identity before use
Function
Skin conditioning / hair conditioning (indole–amino acid conjugate)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not on FDA prohibited/restricted lists (21 CFR 700); no CIR monograph published

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual CAS numbers in commercial databases — verify molecular identity. No CIR or SCCS opinion. MoS cannot be calculated without dermal penetration and NOAEL data.

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Concern Level: Moderate

Frequently Asked Questions

Is Indolebutyroyl Aspartic Acid safe in cosmetics?

Dual CAS numbers in commercial databases — verify molecular identity. No CIR or SCCS opinion. MoS cannot be calculated without dermal penetration and NOAEL data. The EU classifies Indolebutyroyl Aspartic Acid as "permitted". Safety rating: MODERATE.

Is Indolebutyroyl Aspartic Acid allowed in the EU?

Indolebutyroyl Aspartic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Indolebutyroyl Aspartic Acid do in cosmetics?

Indolebutyroyl Aspartic Acid functions as: Skin conditioning / hair conditioning (indole–amino acid conjugate). It is classified as a cosmetic ingredient in our database. CAS number: 101289-65-0 ; alternate listing 73211-20-8 — confirm identity before use.

What is the Margin of Safety for Indolebutyroyl Aspartic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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