Inosine

INCI: INOSINE

CAS Number
58-63-9
Function
Skin conditioning; skin protecting
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not on FDA prohibited/restricted lists (21 CFR 700)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Minimal concerns. Endogenous purine nucleoside with well-understood biochemistry. GHS R36/37/38 applies to pure powder handling, not finished cosmetic concentrations.

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Concern Level: Low

Frequently Asked Questions

Is Inosine safe in cosmetics?

Minimal concerns. Endogenous purine nucleoside with well-understood biochemistry. GHS R36/37/38 applies to pure powder handling, not finished cosmetic concentrations. The EU classifies Inosine as "permitted". Safety rating: GOOD.

Is Inosine allowed in the EU?

Inosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Inosine do in cosmetics?

Inosine functions as: Skin conditioning; skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 58-63-9.

What is the Margin of Safety for Inosine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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