Ionone

INCI: IONONE

CAS Number
8013-90-9 (mixed isomers); 14901-07-6 (β-ionone); 127-41-3 (α-ionone)
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — GRAS for flavoring (21 CFR 182.60); no specific cosmetic restriction under 21 CFR 700–740

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

β-Ionone showed some local respiratory irritation in studies; skin irritation possible at high concentrations; ionone derivatives flagged in fragrance allergen review but not ionone itself; IFRA use-level restrictions apply

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Ionone safe in cosmetics?

β-Ionone showed some local respiratory irritation in studies; skin irritation possible at high concentrations; ionone derivatives flagged in fragrance allergen review but not ionone itself; IFRA use-level restrictions apply The EU classifies Ionone as "permitted". Safety rating: GOOD.

Is Ionone allowed in the EU?

Ionone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ionone do in cosmetics?

Ionone functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 8013-90-9 (mixed isomers); 14901-07-6 (β-ionone); 127-41-3 (α-ionone).

What is the Margin of Safety for Ionone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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