Isoamyl Crotonate

INCI: ISOAMYL CROTONATE

CAS Number
25415-77-4 [^1_14]
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted — not prohibited under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

α,β-unsaturated ester structure warrants attention for potential Michael-acceptor reactivity; limited direct toxicological data compared to saturated analogs

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Isoamyl Crotonate safe in cosmetics?

α,β-unsaturated ester structure warrants attention for potential Michael-acceptor reactivity; limited direct toxicological data compared to saturated analogs The EU classifies Isoamyl Crotonate as "prohibited". Safety rating: MODERATE.

Is Isoamyl Crotonate allowed in the EU?

Isoamyl Crotonate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoamyl Crotonate do in cosmetics?

Isoamyl Crotonate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 25415-77-4 [^1_14].

What is the Margin of Safety for Isoamyl Crotonate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Isoamyl Crotonate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isoamyl Crotonate in your formulation.