Isobutyl Butyrate

INCI: ISOBUTYL BUTYRATE

CAS Number
539-90-2 [^1_5]
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS; no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Flammable liquid; Cramer Class I; not genotoxic; not PBT

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isobutyl Butyrate safe in cosmetics?

Flammable liquid; Cramer Class I; not genotoxic; not PBT The EU classifies Isobutyl Butyrate as "permitted". Safety rating: GOOD.

Is Isobutyl Butyrate allowed in the EU?

Isobutyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Butyrate do in cosmetics?

Isobutyl Butyrate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 539-90-2 [^1_5].

What is the Margin of Safety for Isobutyl Butyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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