Is Isobutyl Heptylate safe in cosmetics?
Isobutyl Heptylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Isobutyl Heptylate
Also known as: 1-02-00-00145, BRN 1760201, EINECS 231-940-1, FEMA No. 2200, Isobutyl heptoate (+3 more)
INCI: ISOBUTYL HEPTYLATE
Isobutyl Heptylate (CAS 7779-80-8) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 7779-80-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-methylpropyl heptanoate
InChIKey
HXJOYVPESRRCDB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed in cosmetics; also recognized as a food substance (FEMA 2200) under 21 CFR 172.515
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isobutyl Heptylate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1350 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
172
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ISOBUTYL HEPTANOATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Isobutyl Heptylate.
Regulatory Flags
fragrance-component
fda_food_additive
Known Synonyms
1-02-00-00145
BRN 1760201
EINECS 231-940-1
FEMA No. 2200
Isobutyl heptoate
2-Methylpropyl heptanoate
2-Methyl-1-propyl heptanoate
UNII-LJS6KH0B8M
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ISOBUTYL HEPTANOATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Isobutyl Heptylate allowed in the EU?
Isobutyl Heptylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isobutyl Heptylate do in cosmetics?
Isobutyl Heptylate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 7779-80-8.
Is Isobutyl Heptylate used outside cosmetics?
Isobutyl Heptylate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isobutyl Heptylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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