Isocyclocitral

INCI: ISOCYCLOCITRAL

CAS Number
1335-66-6 (mixture) / 1423-46-7 (specific isomer)
Function
Fragrance ingredient with aldehydic, green, herbaceous odor
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted subject to IFRA standards; no specific FDA prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Confirmed sensitizer per RIFM/LLNA with IFRA use level restrictions by product category; not genotoxic or photoirritating; respiratory toxicity below TTC threshold.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Isocyclocitral safe in cosmetics?

Confirmed sensitizer per RIFM/LLNA with IFRA use level restrictions by product category; not genotoxic or photoirritating; respiratory toxicity below TTC threshold. The EU classifies Isocyclocitral as "restricted". Safety rating: MODERATE.

Is Isocyclocitral allowed in the EU?

Isocyclocitral EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isocyclocitral do in cosmetics?

Isocyclocitral functions as: Fragrance ingredient with aldehydic, green, herbaceous odor. It is classified as a cosmetic ingredient in our database. CAS number: 1335-66-6 (mixture) / 1423-46-7 (specific isomer).

What is the Margin of Safety for Isocyclocitral?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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