Is Isocyclocitral safe in cosmetics?
Isocyclocitral has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Isocyclocitral
INCI: ISOCYCLOCITRAL
Isocyclocitral (CAS 1335-66-6 (mixture) / 1423-46-7 (specific isomer)) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient with aldehydic, green, herbaceous odor. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1335-66-6 (mixture) / 1423-46-7 (specific isomer) →
Auto-generated CPSR Part A draft with source citations
CAS Number
1335-66-6 (mixture) / 1423-46-7 (specific isomer)
View industrial chemical safety profile →
Function
Fragrance ingredient with aldehydic, green, herbaceous odor
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted subject to IFRA standards; no specific FDA prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isocyclocitral.
Calculate MoS for your specific formulation with the MoS Calculator.
IFRA Concentration Limits (12 Product Categories)
International Fragrance Association standards per product category. Restriction: Restriction. Effective: 2021-02-10.
| Category | Max % | Category | Max % |
|---|---|---|---|
| 1 (Lip products) | 0.1% | 7a (Deodorant – not spray) | 0.2% |
| 2 (Body spray) | 0.03% | 7b (Deodorant spray) | 0.2% |
| 3 (Body cream) | 0.1% | 8 (Face cream) | 0.033% |
| 4 (Fine fragrance) | 0.4% | 9 (Soap) | 0.5% |
| 5a (Body lotion) | 0.1% | 10a (Household – non-spray) | 0.5% |
| 5b (Face cream leave-on) | 0.1% | 10b (Household – spray) | No Restriction% |
| 5c (Hand cream) | 0.1% | 11a (Intimate – leave-on) | 0.033% |
| 5d (Baby cream) | 0.033% | 11b (Intimate – rinse) | 0.033% |
| 6 (Mouthwash) | 0.1% | 12 (Not for consumer exposure) | No Restriction% |
Expert Verdict
Expert safety assessment and concern-level summary for Isocyclocitral.
Regulatory Flags
potential-allergen
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
Frequently Asked Questions
Is Isocyclocitral allowed in the EU?
Isocyclocitral EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isocyclocitral do in cosmetics?
Isocyclocitral functions as: Fragrance ingredient with aldehydic, green, herbaceous odor. It is classified as a cosmetic ingredient in our database. CAS number: 1335-66-6 (mixture) / 1423-46-7 (specific isomer).
Compliance Tools
Check Isocyclocitral compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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