Is Isodecyl Neopentanoate safe in cosmetics?
Isodecyl Neopentanoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Isodecyl Neopentanoate
Also known as: Ceraphyl SLK, DUB VIC-10, Dermol 105, Propanoic acid, 2,2-dimethyl-, isodecyl ester, Isodecyl pivalate (+7 more)
INCI: ISODECYL NEOPENTANOATE
Isodecyl Neopentanoate (CAS 60209-82-7) is a cosmetic emollient functioning as Emollient. Reported NOAEL =5500 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 60209-82-7 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
8-methylnonyl 2,2-dimethylpropanoate
InChIKey
KGKQNDQDVZQTAG-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isodecyl Neopentanoate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Isodecyl Neopentanoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =5500 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =6000 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
comedogenicity_detail
{"comedogenicity_rating": "1", "irritancy_rating": "0", "skin_type_suitability": "all,oily,combination,normal,acne-prone", "acne_safe": "yes", "source": "Light ester"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Isodecyl Neopentanoate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isodecyl Neopentanoate by CAS number or substance name.
Studies
2
Lowest NOAEL
5500 mg/kg bw/day
Highest NOAEL
6000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Ceraphyl SLK
DUB VIC-10
Dermol 105
Propanoic acid, 2,2-dimethyl-, isodecyl ester
Isodecyl pivalate
Neolight 100P
Schercemol 105
Pivalate d'isodecyle
Isodecylpivalat
pivalato de isodecilo
EINECS 262-108-6
UNII-W60VYE24XC
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isodecyl Neopentanoate allowed in the EU?
Isodecyl Neopentanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isodecyl Neopentanoate do in cosmetics?
Isodecyl Neopentanoate functions as: Emollient. It is classified as a Emollient in our database. CAS number: 60209-82-7.
What is the NOAEL for Isodecyl Neopentanoate?
The NOAEL (No Observed Adverse Effect Level) for Isodecyl Neopentanoate is =5500 mg/kg bw/day based on a chronic study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Isodecyl Neopentanoate used outside cosmetics?
Isodecyl Neopentanoate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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