Moderate Cosmetic Ingredient NOAEL Data

Isononyl Alcohol

Also known as: EINECS 248-471-3

INCI: ISONONYL ALCOHOL

Isononyl Alcohol (CAS 27458-94-2) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. NOAEL 144 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 27458-94-2 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C9H20O
MW
144.25 g/mol
EC Number
248-471-3
PubChem CID
17072
IUPAC Name
7-methyloctan-1-ol
InChIKey
QDTDKYHPHANITQ-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Allowed - no specific prohibitions. Reviewed as a fragrance material

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Isononyl Alcohol.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Isononyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =144 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Isononyl Alcohol across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List

Expert Verdict

Expert safety assessment and concern-level summary for Isononyl Alcohol.

Regulatory Flags

fragrance-component ifra_fragrance

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Isononyl Alcohol by CAS number or substance name.

Studies
1
Lowest NOAEL
144 mg/kg bw/day
Highest NOAEL
144 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

EINECS 248-471-3

Chemical Function

Fragrance

Regulatory Lists

IFRA Transparency

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Isononyl Alcohol safe in cosmetics?

Isononyl Alcohol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Isononyl Alcohol allowed in the EU?

Isononyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isononyl Alcohol do in cosmetics?

Isononyl Alcohol functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 27458-94-2.

What is the NOAEL for Isononyl Alcohol?

The NOAEL (No Observed Adverse Effect Level) for Isononyl Alcohol is =144 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Isononyl Alcohol used outside cosmetics?

Isononyl Alcohol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Isononyl Alcohol have different safety status in cosmetics vs industrial chemicals?

Isononyl Alcohol is classified GHS Danger (H315, H318, H319, H412) in the chemicals database but is allowed in EU cosmetics.

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