Moderate Cosmetic Ingredient NOAEL Data

Isononyl Alcohol

INCI: ISONONYL ALCOHOL

CAS Number
27458-94-2
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibitions. Reviewed as a fragrance material

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Isononyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 144 mg/kg bw/day oral rat oral REACH

Expert Verdict

A branched-chain C9 saturated alcohol; toxicological and dermatological evaluation shows low concern when used at typical fragrance concentrations. Used in small amounts only. A nine-carbon primary branched alcohol (molecular formula Cโ‚‰Hโ‚‚โ‚€O). Also serves as a chemical precursor for other cosmetic esters such as isononyl isononanoate and isononyl ferulate. Produced industrially via hydroformylation of octenes

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Concern Level: High

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Isononyl Alcohol safe in cosmetics?

A branched-chain C9 saturated alcohol; toxicological and dermatological evaluation shows low concern when used at typical fragrance concentrations. Used in small amounts only. A nine-carbon primary branched alcohol (molecular formula Cโ‚‰Hโ‚‚โ‚€O). Also serves as a chemical precursor for other cosmetic esters such as isononyl isononanoate and isononyl ferulate. Produced industrially via hydroformylation of octenes The EU classifies Isononyl Alcohol as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Isononyl Alcohol allowed in the EU?

Isononyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isononyl Alcohol do in cosmetics?

Isononyl Alcohol functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 27458-94-2.

What is the Margin of Safety for Isononyl Alcohol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Isononyl Alcohol?

The NOAEL (No Observed Adverse Effect Level) for Isononyl Alcohol is 144 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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