Is Isopropyl Benzoate safe in cosmetics?
Isopropyl Benzoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Isopropyl Benzoate
Also known as: Benzoic acid, 1-methylethyl ester, 4-09-00-00289, BRN 2044384, EINECS 213-361-6, FEMA No. 2932 (+3 more)
INCI: ISOPROPYL BENZOATE
Isopropyl Benzoate (CAS 939-48-0) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, skin conditioning agent, emollient, solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 939-48-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient, skin conditioning agent, emollient, solvent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
propan-2-yl benzoate
InChIKey
FEXQDZTYJVXMOS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FDA approved as flavoring agent (21 CFR 172.515); FEMA GRAS
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isopropyl Benzoate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
No longer valid
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
855
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
1-METHYLETHYL BENZOATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ISOPROPYL BENZOATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/73 | FAS 48-JECFA 57/227
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Preservative
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Isopropyl Benzoate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isopropyl Benzoate by CAS number or substance name.
Studies
18
Lowest NOAEL
40 mg/kg bw/day
Highest NOAEL
3145 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Benzoic acid, 1-methylethyl ester
4-09-00-00289
BRN 2044384
EINECS 213-361-6
FEMA No. 2932
1-Methylethyl benzoate
Isopropylester kyseliny benzoove
UNII-1Q2618834N
Chemical Function
Preservative
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BENZOIC ACID 1-METHYLETHYL ESTER
ChEMBL ID
CHEMBL2260721
Frequently Asked Questions
Is Isopropyl Benzoate allowed in the EU?
Isopropyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropyl Benzoate do in cosmetics?
Isopropyl Benzoate functions as: Fragrance ingredient, skin conditioning agent, emollient, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 939-48-0.
Is Isopropyl Benzoate used outside cosmetics?
Isopropyl Benzoate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isopropyl Benzoate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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