Isopropyl-Dimethyl-Dioxane

INCI: ISOPROPYL-DIMETHYL-DIOXANE

CAS Number
Requires verification (likely 4359-48-8 for 2-isopropyl-5,5-dimethyl-1,3-dioxane — confirm via CosIng) [^1_8]
Function
Fragrance (perfuming agent)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted - not specifically restricted; however, verify no residual 1,4-dioxane contamination per FDA guidance

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

This is a 1,3-dioxane acetal, not 1,4-dioxane (CAS 123-91-1, which is prohibited). Include explicit structural clarification in CPSR submission and verify CAS before regulatory filing.

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Isopropyl-Dimethyl-Dioxane safe in cosmetics?

This is a 1,3-dioxane acetal, not 1,4-dioxane (CAS 123-91-1, which is prohibited). Include explicit structural clarification in CPSR submission and verify CAS before regulatory filing. The EU classifies Isopropyl-Dimethyl-Dioxane as "permitted". Safety rating: MODERATE.

Is Isopropyl-Dimethyl-Dioxane allowed in the EU?

Isopropyl-Dimethyl-Dioxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl-Dimethyl-Dioxane do in cosmetics?

Isopropyl-Dimethyl-Dioxane functions as: Fragrance (perfuming agent). It is classified as a cosmetic ingredient in our database. CAS number: Requires verification (likely 4359-48-8 for 2-isopropyl-5,5-dimethyl-1,3-dioxane — confirm via CosIng) [^1_8].

What is the Margin of Safety for Isopropyl-Dimethyl-Dioxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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