Moderate Cosmetic Ingredient NOAEL Data

Isopropyl Lauroyl Sarcosinate

INCI: ISOPROPYL LAUROYL SARCOSINATE

CAS Number
230309-38-3
Function
Lightweight emollient, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Isopropyl Lauroyl Sarcosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 200 mg/kg bw/day oral rat oral REACH
NOAEL 200 mg/kg bw/day oral code:3544 oral REACH

Expert Verdict

Very limited independent safety data beyond supplier literature; sarcosinate moiety is generally well-tolerated but a formal CIR or SCCS review is not available for this specific INCI; recommend requesting supplier tox dossier for CPSR support

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Concern Level: Moderate

Frequently Asked Questions

Is Isopropyl Lauroyl Sarcosinate safe in cosmetics?

Very limited independent safety data beyond supplier literature; sarcosinate moiety is generally well-tolerated but a formal CIR or SCCS review is not available for this specific INCI; recommend requesting supplier tox dossier for CPSR support The EU classifies Isopropyl Lauroyl Sarcosinate as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Isopropyl Lauroyl Sarcosinate allowed in the EU?

Isopropyl Lauroyl Sarcosinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Lauroyl Sarcosinate do in cosmetics?

Isopropyl Lauroyl Sarcosinate functions as: Lightweight emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 230309-38-3.

What is the Margin of Safety for Isopropyl Lauroyl Sarcosinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Isopropyl Lauroyl Sarcosinate?

The NOAEL (No Observed Adverse Effect Level) for Isopropyl Lauroyl Sarcosinate is 200 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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