Isopropyl Linoleate

INCI: ISOPROPYL LINOLEATE

CAS Number
22882-95-7
Function
Emollient, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR initially found insufficient data (1992); subsequently reviewed under Amended Alkyl Esters assessment (2012) and found safe when formulated to be non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Linoleate chain is susceptible to oxidative degradation and requires antioxidant protection such as tocopherol; classified as slight ocular and slight skin irritant when undiluted; CIR originally requested additional sensitization, irritation, and genotoxicity data.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Isopropyl Linoleate safe in cosmetics?

Linoleate chain is susceptible to oxidative degradation and requires antioxidant protection such as tocopherol; classified as slight ocular and slight skin irritant when undiluted; CIR originally requested additional sensitization, irritation, and genotoxicity data. The EU classifies Isopropyl Linoleate as "restricted". Safety rating: MODERATE.

Is Isopropyl Linoleate allowed in the EU?

Isopropyl Linoleate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Linoleate do in cosmetics?

Isopropyl Linoleate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 22882-95-7.

What is the Margin of Safety for Isopropyl Linoleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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