Isopropyl Methoxycinnamate

INCI: ISOPROPYL METHOXYCINNAMATE

CAS Number
5466-76-2
Function
UV absorber (cinnamate-class)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not listed in 21 CFR 352 (OTC sunscreen monograph); not approved as sunscreen active in the US

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cinnamate with photoallergy risk and cross-reactivity potential; phototoxicity testing mandatory if used; concentration and justification must be robustly defended in CPSR.

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Concern Level: High

Frequently Asked Questions

Is Isopropyl Methoxycinnamate safe in cosmetics?

Cinnamate with photoallergy risk and cross-reactivity potential; phototoxicity testing mandatory if used; concentration and justification must be robustly defended in CPSR. The EU classifies Isopropyl Methoxycinnamate as "permitted". Safety rating: MODERATE.

Is Isopropyl Methoxycinnamate allowed in the EU?

Isopropyl Methoxycinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Methoxycinnamate do in cosmetics?

Isopropyl Methoxycinnamate functions as: UV absorber (cinnamate-class). It is classified as a cosmetic ingredient in our database. CAS number: 5466-76-2.

What is the Margin of Safety for Isopropyl Methoxycinnamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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