Regulatory Status
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Safety Data
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Expert Verdict
Key concern: Acrylamide monomer residuals - acrylamide is a Category 2 carcinogen and neurotoxin; the polymerized form (polyNIPAM) is considered safe, but free monomer must be minimized; potential skin irritant in monomeric form. Also known as NIPAM (N-Isopropylacrylamide); the derived polymer poly(NIPAM) exhibits a lower critical solution temperature (LCST) around 32°C, making it thermoresponsive - it's used in tissue engineering, drug delivery, and smart cosmetic delivery systems
Frequently Asked Questions
Is Isopropylacrylamide safe in cosmetics?
Key concern: Acrylamide monomer residuals - acrylamide is a Category 2 carcinogen and neurotoxin; the polymerized form (polyNIPAM) is considered safe, but free monomer must be minimized; potential skin irritant in monomeric form. Also known as NIPAM (N-Isopropylacrylamide); the derived polymer poly(NIPAM) exhibits a lower critical solution temperature (LCST) around 32°C, making it thermoresponsive - it's used in tissue engineering, drug delivery, and smart cosmetic delivery systems The EU classifies Isopropylacrylamide as "prohibited". Safety rating: MODERATE.
Is Isopropylacrylamide allowed in the EU?
Isopropylacrylamide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropylacrylamide do in cosmetics?
Isopropylacrylamide functions as: Monomer / film-forming / hair-fixing (used as building block for poly(NIPAM) polymers). It is classified as a cosmetic ingredient in our database. CAS number: 2210-25-5.
What is the Margin of Safety for Isopropylacrylamide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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