Is Keratinase safe in cosmetics?
Keratinase has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Keratinase
INCI: KERATINASE
Keratinase (CAS 9025-41-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning (proteolytic enzyme). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Function
Skin conditioning (proteolytic enzyme)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Keratinase.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Keratinase — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Keratinase allowed in the EU?
Keratinase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Keratinase do in cosmetics?
Keratinase functions as: Skin conditioning (proteolytic enzyme). It is classified as a cosmetic ingredient in our database. CAS number: 9025-41-6.
Compliance Tools
Check Keratinase compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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