Kigelia Africana Leaf Extract

INCI: KIGELIA AFRICANA LEAF EXTRACT

CAS Number
223749-33-7
Function
Skin conditioning (firming, anti-inflammatory, anti-aging); contains steroidal saponins, flavonoids, naphthoquinones
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not specifically restricted under 21 CFR; general cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains estrogen-like compounds with potential endocrine activity requiring assessment in CPSR; limited published dermal toxicological data; supplier COA should confirm absence of pyrrolizidine alkaloids; recommend patch testing at use level

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Kigelia Africana Leaf Extract safe in cosmetics?

Contains estrogen-like compounds with potential endocrine activity requiring assessment in CPSR; limited published dermal toxicological data; supplier COA should confirm absence of pyrrolizidine alkaloids; recommend patch testing at use level The EU classifies Kigelia Africana Leaf Extract as "permitted". Safety rating: MODERATE.

Is Kigelia Africana Leaf Extract allowed in the EU?

Kigelia Africana Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Kigelia Africana Leaf Extract do in cosmetics?

Kigelia Africana Leaf Extract functions as: Skin conditioning (firming, anti-inflammatory, anti-aging); contains steroidal saponins, flavonoids, naphthoquinones. It is classified as a cosmetic ingredient in our database. CAS number: 223749-33-7.

What is the Margin of Safety for Kigelia Africana Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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