Lactobacillus/Papaya Fruit Ferment Extract

INCI: LACTOBACILLUS/PAPAYA FRUIT FERMENT EXTRACT

CAS Number
These complex biotechnology-derived fermentation products typically lack individual CAS registry numbers. The base ingredient Lactobacillus Ferment has CAS 1686112-36-6 and 68333-16-4, but the substrate-specific variants listed here have no assigned CAS.
Function
Abrasive (enzymatic exfoliation), Hair Conditioning, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Lactobacillus fermentation postbiotics demonstrate tyrosinase-inhibitory activity (72.1% inhibition in vitro, exceeding 2 mM kojic acid). The CIR Panel warned that these ingredients should not be used at concentrations that cause skin depigmentation, as this would constitute a drug effect. <span style="display:none"></span>. Papaya (Carica papaya) provides natural papain enzyme, which acts as a gentle biological exfoliant. Fermentation with Lactobacillus enhances the enzymatic activity and pr...

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Lactobacillus/Papaya Fruit Ferment Extract safe in cosmetics?

Lactobacillus fermentation postbiotics demonstrate tyrosinase-inhibitory activity (72.1% inhibition in vitro, exceeding 2 mM kojic acid). The CIR Panel warned that these ingredients should not be used at concentrations that cause skin depigmentation, as this would constitute a drug effect. <span style="display:none"></span>. Papaya (Carica papaya) provides natural papain enzyme, which acts as a gentle biological exfoliant. Fermentation with Lactobacillus enhances the enzymatic activity and pr... The EU classifies Lactobacillus/Papaya Fruit Ferment Extract as "permitted". Safety rating: MODERATE.

Is Lactobacillus/Papaya Fruit Ferment Extract allowed in the EU?

Lactobacillus/Papaya Fruit Ferment Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lactobacillus/Papaya Fruit Ferment Extract do in cosmetics?

Lactobacillus/Papaya Fruit Ferment Extract functions as: Abrasive (enzymatic exfoliation), Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: These complex biotechnology-derived fermentation products typically lack individual CAS registry numbers. The base ingredient Lactobacillus Ferment has CAS 1686112-36-6 and 68333-16-4, but the substrate-specific variants listed here have no assigned CAS..

What is the Margin of Safety for Lactobacillus/Papaya Fruit Ferment Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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