Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract

INCI: LACTOBACILLUS/SACCHAROMYCES/REHMANNIA GLUTINOSA ROOT FERMENT EXTRACT

CAS Number
Not assigned
Function
Skin Conditioning, Moisturizing (based on Rehmannia's iridoid glycoside and polysaccharide profile)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Rehmannia glutinosa (Di Huang) is generally well-tolerated topically; contains catalpol and other iridoid glycosides - limited dermal toxicity data specific to fermented form; potential for batch variability in bioactive concentrations. Rehmannia is one of the most important herbs in TCM and Korean medicine (used in the classic "Six-Flavor Rehmannia Pill"); rich in catalpol, rehmannioside, and polysaccharides; fermentation may convert catalpol into aucubin derivatives with enhanced antioxidan...

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract safe in cosmetics?

Rehmannia glutinosa (Di Huang) is generally well-tolerated topically; contains catalpol and other iridoid glycosides - limited dermal toxicity data specific to fermented form; potential for batch variability in bioactive concentrations. Rehmannia is one of the most important herbs in TCM and Korean medicine (used in the classic "Six-Flavor Rehmannia Pill"); rich in catalpol, rehmannioside, and polysaccharides; fermentation may convert catalpol into aucubin derivatives with enhanced antioxidan... The EU classifies Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract as "permitted". Safety rating: MODERATE.

Is Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract allowed in the EU?

Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract do in cosmetics?

Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract functions as: Skin Conditioning, Moisturizing (based on Rehmannia's iridoid glycoside and polysaccharide profile). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Lactobacillus/Saccharomyces/Rehmannia Glutinosa Root Ferment Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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