Lactoferricin

INCI: LACTOFERRICIN

CAS Number
141879-60-3 (bovine lactoferricin B)
Function
Antimicrobial peptide; skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted under 21 CFR 700; no CIR monograph exists specifically for lactoferricin

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited cosmetic-use safety data with no CIR or SCCS monograph; bovine origin requires BSE/TSE compliance; potential cross-reactivity in milk-allergic individuals; antimicrobial activity may disrupt skin microbiome at high concentrations.

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Concern Level: Moderate

Frequently Asked Questions

Is Lactoferricin safe in cosmetics?

Limited cosmetic-use safety data with no CIR or SCCS monograph; bovine origin requires BSE/TSE compliance; potential cross-reactivity in milk-allergic individuals; antimicrobial activity may disrupt skin microbiome at high concentrations. The EU classifies Lactoferricin as "permitted". Safety rating: MODERATE.

Is Lactoferricin allowed in the EU?

Lactoferricin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lactoferricin do in cosmetics?

Lactoferricin functions as: Antimicrobial peptide; skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 141879-60-3 (bovine lactoferricin B).

What is the Margin of Safety for Lactoferricin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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