Laur/Myrist/Palmitamidobutyl Guanidine Acetate

INCI: LAUR/MYRIST/PALMITAMIDOBUTYL GUANIDINE ACETATE

CAS Number
Mixture - no single CAS. Component CAS numbers include 161865-39-0 (lauramidobutyl guanidine acetate) and 499222-93-4 (palmitamidobutyl guanidine acetate)
Function
Antimicrobial preservative. This is a guanidine-based cationic compound used for microbial protection in cosmetic formulations
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Not specifically prohibited; safety substantiation required by manufacturer

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published safety data in public literature. The guanidine moiety is inherently cationic and may present irritation potential at higher concentrations. As a mixture of C12/C14/C16 chain-length homologues, batch variability in chain-length distribution could affect performance and safety profiles. Combines lauroyl (C12), myristoyl (C14), and palmitoyl (C16) fatty acid chains linked to an aminobutyl guanidine head group, delivered as the acetate salt. The mixed chain-length composition b...

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

preservative

Frequently Asked Questions

Is Laur/Myrist/Palmitamidobutyl Guanidine Acetate safe in cosmetics?

Limited published safety data in public literature. The guanidine moiety is inherently cationic and may present irritation potential at higher concentrations. As a mixture of C12/C14/C16 chain-length homologues, batch variability in chain-length distribution could affect performance and safety profiles. Combines lauroyl (C12), myristoyl (C14), and palmitoyl (C16) fatty acid chains linked to an aminobutyl guanidine head group, delivered as the acetate salt. The mixed chain-length composition b... The EU classifies Laur/Myrist/Palmitamidobutyl Guanidine Acetate as "permitted". Safety rating: MODERATE.

Is Laur/Myrist/Palmitamidobutyl Guanidine Acetate allowed in the EU?

Laur/Myrist/Palmitamidobutyl Guanidine Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Laur/Myrist/Palmitamidobutyl Guanidine Acetate do in cosmetics?

Laur/Myrist/Palmitamidobutyl Guanidine Acetate functions as: Antimicrobial preservative. This is a guanidine-based cationic compound used for microbial protection in cosmetic formulations. It is classified as a cosmetic ingredient in our database. CAS number: Mixture - no single CAS. Component CAS numbers include 161865-39-0 (lauramidobutyl guanidine acetate) and 499222-93-4 (palmitamidobutyl guanidine acetate).

What is the Margin of Safety for Laur/Myrist/Palmitamidobutyl Guanidine Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Laur/Myrist/Palmitamidobutyl Guanidine Acetate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Laur/Myrist/Palmitamidobutyl Guanidine Acetate in your formulation.