Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Lauroyl Sarcosine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=2 other | oral | rat | oral | REACH |
| NOEL | 30 mg/kg bw/day | oral | rat | oral | REACH |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
the Panel published a safety assessment with the conclusion that 5 fatty acyl sarcosines and 5 sarcosinate salts are safe as used in rinse-off products, safe for use in leave-on products at concentrations of ≤5%, and the data are insufficient to determine the safety for use in products where the fatty acyl sarcosines and
the Panel published a safety assessment with the conclusion that 5 fatty acyl sarcosines and 5 sarcosinate salts are safe as used in rinse-off products, safe for use in leave-on products at concentrations of ≤5%, and the data are insufficient to determine the safety for use in products where the fatty acyl sarcosines and
Expert Verdict
Secondary amine surfactant with risk of N-nitroso compound formation when combined with nitrosating agents; safe in rinse-off and leave-on products up to 5%, but inhalation safety not established; avoid spray/aerosol formats.
Frequently Asked Questions
Is Lauroyl Sarcosine safe in cosmetics?
Secondary amine surfactant with risk of N-nitroso compound formation when combined with nitrosating agents; safe in rinse-off and leave-on products up to 5%, but inhalation safety not established; avoid spray/aerosol formats. The EU classifies Lauroyl Sarcosine as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Lauroyl Sarcosine allowed in the EU?
Lauroyl Sarcosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lauroyl Sarcosine do in cosmetics?
Lauroyl Sarcosine functions as: Surfactant — cleansing agent, hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 97-78-9.
What is the Margin of Safety for Lauroyl Sarcosine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Lauroyl Sarcosine?
The NOAEL (No Observed Adverse Effect Level) for Lauroyl Sarcosine is >=2 other based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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