Lepidium Meyenii Root Extract

INCI: LEPIDIUM MEYENII ROOT EXTRACT

CAS Number
828927-86-2
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-characterized safety profile supported by extensive dietary supplement use history; no significant dermal irritation or sensitization documented at cosmetic use levels. Root-specific extract concentrates the hypocotyl bioactives including macamides (fatty acid amides), macaenes (polyunsaturated compounds), and unique imidazole alkaloids (lepidiline A and B); traditionally used at high altitude in Peru and valued for adaptogenic and energizing properties now translated to cosmetic "skin e...

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Lepidium Meyenii Root Extract safe in cosmetics?

Well-characterized safety profile supported by extensive dietary supplement use history; no significant dermal irritation or sensitization documented at cosmetic use levels. Root-specific extract concentrates the hypocotyl bioactives including macamides (fatty acid amides), macaenes (polyunsaturated compounds), and unique imidazole alkaloids (lepidiline A and B); traditionally used at high altitude in Peru and valued for adaptogenic and energizing properties now translated to cosmetic "skin e... The EU classifies Lepidium Meyenii Root Extract as "permitted". Safety rating: MODERATE.

Is Lepidium Meyenii Root Extract allowed in the EU?

Lepidium Meyenii Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lepidium Meyenii Root Extract do in cosmetics?

Lepidium Meyenii Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 828927-86-2.

What is the Margin of Safety for Lepidium Meyenii Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Lepidium Meyenii Root Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Lepidium Meyenii Root Extract in your formulation.