Ligninase

INCI: LIGNINASE

CAS Number
42613-30-9 (lignin peroxidase)
Function
Skin conditioning (enzyme-based)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no prohibition or restriction; enzymes in cosmetics are generally permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

As a peroxidase enzyme, potential for skin irritation at high concentrations; must be formulated at appropriate activity levels; enzyme stability and pH sensitivity require careful formulation. A peroxidase enzyme that degrades lignin in nature; in cosmetics, used for enzymatic conditioning and potential antioxidant activity; requires hydrogen peroxide as co-substrate in its native mechanism

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Concern Level: Moderate

Frequently Asked Questions

Is Ligninase safe in cosmetics?

As a peroxidase enzyme, potential for skin irritation at high concentrations; must be formulated at appropriate activity levels; enzyme stability and pH sensitivity require careful formulation. A peroxidase enzyme that degrades lignin in nature; in cosmetics, used for enzymatic conditioning and potential antioxidant activity; requires hydrogen peroxide as co-substrate in its native mechanism The EU classifies Ligninase as "permitted". Safety rating: MODERATE.

Is Ligninase allowed in the EU?

Ligninase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ligninase do in cosmetics?

Ligninase functions as: Skin conditioning (enzyme-based). It is classified as a cosmetic ingredient in our database. CAS number: 42613-30-9 (lignin peroxidase).

What is the Margin of Safety for Ligninase?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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