Lithospermum Root Extract Serum Albumin Succinate

INCI: LITHOSPERMUM ROOT EXTRACT SERUM ALBUMIN SUCCINATE (COMPOUND INCI)

CAS Number
Not specifically assigned as a single-CAS complex
Function
Skin conditioning; skin protecting - this is a conjugate/complex ingredient combining lithospermum root extract with succinylated serum albumin to enhance delivery and bioavailability of active compounds
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Serum albumin derivatives and botanical extracts are permitted in cosmetics; the compound is not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Moderate caution warranted. Serum albumin is an animal-derived protein (typically bovine), raising potential allergenicity concerns and BSE/TSE safety considerations. Not suitable for vegan or COSMOS/ECOCERT-certified formulations without verified sourcing. The lithospermum component itself is well-tolerated. This is a protein-botanical conjugate designed for enhanced skin penetration. The succinate modification of serum albumin improves water solubility and acts as a carrier system for litho...

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Lithospermum Root Extract Serum Albumin Succinate safe in cosmetics?

Moderate caution warranted. Serum albumin is an animal-derived protein (typically bovine), raising potential allergenicity concerns and BSE/TSE safety considerations. Not suitable for vegan or COSMOS/ECOCERT-certified formulations without verified sourcing. The lithospermum component itself is well-tolerated. This is a protein-botanical conjugate designed for enhanced skin penetration. The succinate modification of serum albumin improves water solubility and acts as a carrier system for litho... The EU classifies Lithospermum Root Extract Serum Albumin Succinate as "permitted". Safety rating: MODERATE.

Is Lithospermum Root Extract Serum Albumin Succinate allowed in the EU?

Lithospermum Root Extract Serum Albumin Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lithospermum Root Extract Serum Albumin Succinate do in cosmetics?

Lithospermum Root Extract Serum Albumin Succinate functions as: Skin conditioning; skin protecting - this is a conjugate/complex ingredient combining lithospermum root extract with succinylated serum albumin to enhance delivery and bioavailability of active compounds. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned as a single-CAS complex.

What is the Margin of Safety for Lithospermum Root Extract Serum Albumin Succinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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