Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract

INCI: LONICERA JAPONICA FLOWER/ROOT/GLYCYRRHIZA GLABRA EXTRACT

CAS Number
Blend - no single CAS (component CAS numbers: 223749-79-9 for Lonicera japonica; 84775-94-0 for Glycyrrhiza glabra extract)
Function
Skin conditioning, soothing, anti-inflammatory, antimicrobial
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - both components are permitted; licorice extract is also GRAS for food use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Glycyrrhiza glabra contains glycyrrhizin, which in high oral doses can cause hypertension and hypokalemia, but topical cosmetic use at typical concentrations is considered safe. The honeysuckle component has the same paraben-precursor consideration as above. Combines the antimicrobial and anti-inflammatory properties of Japanese honeysuckle with the skin-brightening (via glabridin) and anti-inflammatory (via glycyrrhizin/glycyrrhetinic acid) benefits of licorice root; synergistic calming blen...

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract safe in cosmetics?

Glycyrrhiza glabra contains glycyrrhizin, which in high oral doses can cause hypertension and hypokalemia, but topical cosmetic use at typical concentrations is considered safe. The honeysuckle component has the same paraben-precursor consideration as above. Combines the antimicrobial and anti-inflammatory properties of Japanese honeysuckle with the skin-brightening (via glabridin) and anti-inflammatory (via glycyrrhizin/glycyrrhetinic acid) benefits of licorice root; synergistic calming blen... The EU classifies Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract as "permitted". Safety rating: MODERATE.

Is Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract allowed in the EU?

Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract do in cosmetics?

Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract functions as: Skin conditioning, soothing, anti-inflammatory, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: Blend - no single CAS (component CAS numbers: 223749-79-9 for Lonicera japonica; 84775-94-0 for Glycyrrhiza glabra extract).

What is the Margin of Safety for Lonicera Japonica Flower/Root/Glycyrrhiza Glabra Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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