Luffa Operculata Extract

INCI: LUFFA OPERCULATA EXTRACT

CAS Number
90063-68-6
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Higher caution warranted than other Luffa species. Luffa operculata contains cucurbitacins (triterpene glycosides) that are cytotoxic at elevated concentrations; traditionally used as a potent nasal decongestant in South American folk medicine, which has caused mucosal irritation at high doses; careful concentration control is essential in cosmetic use. Distinct species from L. cylindrica; native to the Americas; the cucurbitacin content gives it biological activity but also a narrower safety...

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Luffa Operculata Extract safe in cosmetics?

Higher caution warranted than other Luffa species. Luffa operculata contains cucurbitacins (triterpene glycosides) that are cytotoxic at elevated concentrations; traditionally used as a potent nasal decongestant in South American folk medicine, which has caused mucosal irritation at high doses; careful concentration control is essential in cosmetic use. Distinct species from L. cylindrica; native to the Americas; the cucurbitacin content gives it biological activity but also a narrower safety... The EU classifies Luffa Operculata Extract as "permitted". Safety rating: MODERATE.

Is Luffa Operculata Extract allowed in the EU?

Luffa Operculata Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Luffa Operculata Extract do in cosmetics?

Luffa Operculata Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90063-68-6.

What is the Margin of Safety for Luffa Operculata Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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