Is Magnesium Sulfate safe in cosmetics?
Magnesium Sulfate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Magnesium Sulfate
Also known as: Caswell No. 534, EINECS 231-298-2, EPA Pesticide Chemical Code 050503, NSC 146179, Sal Angalis (+7 more)
INCI: MAGNESIUM SULFATE
Magnesium Sulfate (CAS 7487-88-9) is a cosmetic cosmetic ingredient functioning as Sitz bath osmotic agent; muscle relaxant; magnesium source. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7487-88-9 →
Auto-generated CPSR Part A draft with source citations
Function
Sitz bath osmotic agent; muscle relaxant; magnesium source
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA limit for cosmetic bath use. GRAS as food additive. OTC drug if specific therapeutic claims (treating infection, wound treatment) are made.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Magnesium Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is mildly irritating to the eyes and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
3 property records from structured ingredient metadata.
acne
{"cas_number": "7487-88-9", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
humectant
{"cas_number": "7487-88-9", "ingredient_class": "hygroscopic_salt", "molecular_weight_Da": "120.37", "chemical_type": "mineral", "water_binding_mechanism": "osmotic/hygroscopic", "water_holding_capacity_g_per_g": "0.2-0.4", "hygroscopicity_at_50_RH": "good", "hygroscopicity_at_80_RH": "excellent", "NMF_component": "no", "NMF_percentage_natural": "0", "TEWL_reduction_pct": "10-18", "skin_hydration_…
mineral_clay
{"cas_number": "7487-88-9", "ingredient_class": "magnesium_compound", "chemical_formula": "MgSO4", "mineral_origin": "natural", "particle_size_range_um": "10-500", "surface_area_m2_per_g": "0.5-5", "crystal_structure": "orthorhombic", "color_appearance": "white", "opacity": "opaque", "refractive_index": "1.52", "oil_absorption_g_per_100g": "80-200", "water_absorption_capacity": "low", "surface_cha…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Filler
Flow promoter
No specific technical function
Pigment
Processing aids not otherwise specified
Softener and conditioner
Viscosity modifier
Regulatory List Membership (3)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Magnesium Sulfate.
Regulatory Flags
sitz-bath
postpartum-care
osmotic-anti-swelling
muscle-relaxation
magnesium-source
leave-on-bath-safe
eu-unrestricted
no-fda-limit
meca-supported
eu_children_restricted
epa_safer_alternative
jecfa_safe
Known Synonyms
Caswell No. 534
EINECS 231-298-2
EPA Pesticide Chemical Code 050503
NSC 146179
Sal Angalis
Sal De sedlitz
Magnesium sulfate in dextrose 5% in plastic container
Magnesium sulfate in plastic container
UNII-ML30MJ2U7I
Magnesii sulfas
MgSO4
magnesium(II) sulfate
Chemical Function
Viscosity modifier
Filler
Softener and conditioner
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
children; Europe; Personal care
children; Europe; Personal care - general moisturizing - hand/body lotion
Europe; Personal care
Europe; Personal care
Europe; Personal care
Canada; pharmaceutical
SCIL (9/2019)
active_ingredient; animal_products; Europe; pharmaceutical; residue
Europe; supplements
Europe; food_additive; supplements
Europe; plastic_additive
inert_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MAGNESIUM SULFATE ANHYDROUS
ChEMBL ID
CHEMBL2021423
Max Phase
4
Adverse Event Associations
2676
Frequently Asked Questions
Is Magnesium Sulfate allowed in the EU?
Magnesium Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Sulfate do in cosmetics?
Magnesium Sulfate functions as: Sitz bath osmotic agent; muscle relaxant; magnesium source. It is classified as a cosmetic ingredient in our database. CAS number: 7487-88-9.
Is Magnesium Sulfate used outside cosmetics?
Magnesium Sulfate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Magnesium Sulfate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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