Mahonia Aquifolium Flower/Leaf/Stem Extract

INCI: MAHONIA AQUIFOLIUM FLOWER/LEAF/STEM EXTRACT

CAS Number
90063-76-6
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. No prohibitions or restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains berberine alkaloids, which can be phototoxic at high concentrations. Generally well-tolerated in cosmetic formulations at standard levels. CIR has reviewed related Mahonia extracts without flagging major safety issues. Derived from Oregon Grape (Mahonia aquifolium, Berberidaceae) - flowers, leaves, and stems. Research-backed antioxidant that helps offset visible effects of sun damage. Contains alkaloids (berberine, berbamine) with documented anti-inflammatory and antimicrobial proper...

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Mahonia Aquifolium Flower/Leaf/Stem Extract safe in cosmetics?

Contains berberine alkaloids, which can be phototoxic at high concentrations. Generally well-tolerated in cosmetic formulations at standard levels. CIR has reviewed related Mahonia extracts without flagging major safety issues. Derived from Oregon Grape (Mahonia aquifolium, Berberidaceae) - flowers, leaves, and stems. Research-backed antioxidant that helps offset visible effects of sun damage. Contains alkaloids (berberine, berbamine) with documented anti-inflammatory and antimicrobial proper... The EU classifies Mahonia Aquifolium Flower/Leaf/Stem Extract as "permitted". Safety rating: MODERATE.

Is Mahonia Aquifolium Flower/Leaf/Stem Extract allowed in the EU?

Mahonia Aquifolium Flower/Leaf/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mahonia Aquifolium Flower/Leaf/Stem Extract do in cosmetics?

Mahonia Aquifolium Flower/Leaf/Stem Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90063-76-6.

What is the Margin of Safety for Mahonia Aquifolium Flower/Leaf/Stem Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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