Moderate Cosmetic Ingredient GHS Classified

Manganese Dioxide

INCI: MANGANESE DIOXIDE

CAS Number
1313-13-9
Function
Antioxidant
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - not specifically prohibited or restricted for cosmetic use; not an FDA-approved color additive

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The aerosol is irritating to the respiratory tract.
Long-term Exposure Effects
The substance may have effects on the lungs and central nervous system. This may result in increased susceptibility to bronchitis, pneumonitis and neurologic and neuropsychiatric disorders (manganism). Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Expert Verdict

Inhalation hazard in powder form (occupational exposure); strong oxidizer - handle carefully during manufacturing; low dermal absorption risk in finished products. Dark brown to black insoluble powder; synthetic origin; potent oxidizing agent; used more for its antioxidant function than as a colorant in cosmetics

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Concern Level: Moderate

Frequently Asked Questions

Is Manganese Dioxide safe in cosmetics?

Inhalation hazard in powder form (occupational exposure); strong oxidizer - handle carefully during manufacturing; low dermal absorption risk in finished products. Dark brown to black insoluble powder; synthetic origin; potent oxidizing agent; used more for its antioxidant function than as a colorant in cosmetics The EU classifies Manganese Dioxide as "permitted". Safety rating: MODERATE.

Is Manganese Dioxide allowed in the EU?

Manganese Dioxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Manganese Dioxide do in cosmetics?

Manganese Dioxide functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 1313-13-9.

What is the Margin of Safety for Manganese Dioxide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Manganese Dioxide compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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