Moderate Cosmetic Ingredient GHS Classified

Sodium Oxide

INCI: SODIUM OXIDE

CAS Number
1313-59-3
Function
Buffering (pH adjuster)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
corr
Hazard Statements
Causes severe skin burns and eye damage
Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes. Medical observation is indicated.
Routes of Exposure
Serious by all routes of exposure.

Expert Verdict

Highly caustic strong alkali (Na₂O); causes severe burns on contact with moisture; must be handled as corrosive; fire risk with combustibles; strictly for formulation pH adjustment at trace levels

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Concern Level: Moderate

Frequently Asked Questions

Is Sodium Oxide safe in cosmetics?

Highly caustic strong alkali (Na₂O); causes severe burns on contact with moisture; must be handled as corrosive; fire risk with combustibles; strictly for formulation pH adjustment at trace levels The EU classifies Sodium Oxide as "restricted". Safety rating: MODERATE.

Is Sodium Oxide allowed in the EU?

Sodium Oxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Oxide do in cosmetics?

Sodium Oxide functions as: Buffering (pH adjuster). It is classified as a cosmetic ingredient in our database. CAS number: 1313-59-3.

What is the Margin of Safety for Sodium Oxide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Is Sodium Oxide classified as hazardous under GHS?

Sodium Oxide carries a GHS signal word of "DANGER". Hazard statements: Causes severe skin burns and eye damage. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.

Compliance Tools

Check Sodium Oxide compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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