Manganese Pyridoxal 5-Phosphate

INCI: MANGANESE PYRIDOXAL 5-PHOSPHATE

CAS Number
Not assigned (listed as "-" in CosIng). The parent compound pyridoxal 5-phosphate has CAS 54-47-7
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited publicly available toxicological data specific to the manganese salt form. The parent compound (pyridoxal 5-phosphate, the active form of vitamin B6) is well-characterized and generally regarded as safe. Combines the skin-conditioning benefits of the biologically active form of vitamin B6 with manganese, which is an essential trace element involved in enzymatic antioxidant defense

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Concern Level: High

Frequently Asked Questions

Is Manganese Pyridoxal 5-Phosphate safe in cosmetics?

Very limited publicly available toxicological data specific to the manganese salt form. The parent compound (pyridoxal 5-phosphate, the active form of vitamin B6) is well-characterized and generally regarded as safe. Combines the skin-conditioning benefits of the biologically active form of vitamin B6 with manganese, which is an essential trace element involved in enzymatic antioxidant defense The EU classifies Manganese Pyridoxal 5-Phosphate as "permitted". Safety rating: MODERATE.

Is Manganese Pyridoxal 5-Phosphate allowed in the EU?

Manganese Pyridoxal 5-Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Manganese Pyridoxal 5-Phosphate do in cosmetics?

Manganese Pyridoxal 5-Phosphate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (listed as "-" in CosIng). The parent compound pyridoxal 5-phosphate has CAS 54-47-7.

What is the Margin of Safety for Manganese Pyridoxal 5-Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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