Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Generally well-tolerated at typical cosmetic use levels; no significant irritation or sensitization reported in topical formulations. A xanthone glucoside (C₁₉H₁₈O₁₁, MW 422.34) with potent antioxidant and anti-inflammatory activity; inhibits collagenase and elastase; scavenges UV-induced ROS; acts as a whitening agent by inhibiting tyrosinase; improves skin barrier function
Regulatory Flags
Frequently Asked Questions
Is Mangiferin safe in cosmetics?
Generally well-tolerated at typical cosmetic use levels; no significant irritation or sensitization reported in topical formulations. A xanthone glucoside (C₁₉H₁₈O₁₁, MW 422.34) with potent antioxidant and anti-inflammatory activity; inhibits collagenase and elastase; scavenges UV-induced ROS; acts as a whitening agent by inhibiting tyrosinase; improves skin barrier function The EU classifies Mangiferin as "permitted". Safety rating: MODERATE.
Is Mangiferin allowed in the EU?
Mangiferin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mangiferin do in cosmetics?
Mangiferin functions as: Skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 4773-96-0.
What is the Margin of Safety for Mangiferin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Mangiferin compliance across multiple jurisdictions:
Related Ingredients
Is Mangiferin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Mangiferin in your formulation.