Also known as: EINECS 285-377-1, Tea tree ext.
INCI: MELALEUCA ALTERNIFOLIA FLOWER/LEAF/STEM EXTRACT
Melaleuca Alternifolia Flower/Leaf/Stem Extract (CAS 85085-48-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning, perfuming. Reported NOAEL =45 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 85085-48-9 →
Melaleuca Alternifolia Flower/Leaf/Stem Extract is classified GHS Danger (H226, H302, H304, H315, H317, H319, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Melaleuca Alternifolia Flower/Leaf/Stem Extract.
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1 study endpoint found for Melaleuca Alternifolia Flower/Leaf/Stem Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =45 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Expert safety assessment and concern-level summary for Melaleuca Alternifolia Flower/Leaf/Stem Extract.
Public NOAEL study rows linked to Melaleuca Alternifolia Flower/Leaf/Stem Extract by CAS number or substance name.
Melaleuca Alternifolia Flower/Leaf/Stem Extract has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Melaleuca Alternifolia Flower/Leaf/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Melaleuca Alternifolia Flower/Leaf/Stem Extract functions as: Skin conditioning, perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 85085-48-9.
The NOAEL (No Observed Adverse Effect Level) for Melaleuca Alternifolia Flower/Leaf/Stem Extract is =45 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Melaleuca Alternifolia Flower/Leaf/Stem Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Melaleuca Alternifolia Flower/Leaf/Stem Extract is classified GHS Danger (H226, H302, H304, H315, H317, H319, H411) in the chemicals database but is allowed in EU cosmetics.
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