Menaquinone-7

INCI: MENAQUINONE-7

CAS Number
2124-57-4
Function
Astringent, anti-sebum, bleaching (skin lightening), skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted for cosmetic use; also has GRAS recognition as vitamin Kโ‚‚ in food/supplements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally well-tolerated; vitamin Kโ‚‚ may interact with anticoagulant medications (warfarin) when ingested - cosmetic topical use presents lower risk; limited long-term topical safety data. All-trans form of vitamin Kโ‚‚ (menaquinone series); naturally produced by bacterial fermentation (Bacillus subtilis natto); multifunctional cosmetic active with emerging evidence for dark-circle reduction and elasticity improvement

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Concern Level: Moderate

Frequently Asked Questions

Is Menaquinone-7 safe in cosmetics?

Generally well-tolerated; vitamin Kโ‚‚ may interact with anticoagulant medications (warfarin) when ingested - cosmetic topical use presents lower risk; limited long-term topical safety data. All-trans form of vitamin Kโ‚‚ (menaquinone series); naturally produced by bacterial fermentation (Bacillus subtilis natto); multifunctional cosmetic active with emerging evidence for dark-circle reduction and elasticity improvement The EU classifies Menaquinone-7 as "permitted". Safety rating: MODERATE.

Is Menaquinone-7 allowed in the EU?

Menaquinone-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Menaquinone-7 do in cosmetics?

Menaquinone-7 functions as: Astringent, anti-sebum, bleaching (skin lightening), skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 2124-57-4.

What is the Margin of Safety for Menaquinone-7?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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