Methionyl rh-Polypeptide-83

INCI: METHIONYL RH-POLYPEPTIDE-83

CAS Number
Not assigned
Function
Skin Conditioning (consistent with rh-Polypeptide class entries in CosIng)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited publicly available safety data; no documented adverse effects; as with all recombinant peptides, patch testing is recommended. Recombinant human polypeptide produced by E. coli fermentation with methionine initiation; extremely low prevalence in commercial products

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Concern Level: Moderate

Frequently Asked Questions

Is Methionyl rh-Polypeptide-83 safe in cosmetics?

Very limited publicly available safety data; no documented adverse effects; as with all recombinant peptides, patch testing is recommended. Recombinant human polypeptide produced by E. coli fermentation with methionine initiation; extremely low prevalence in commercial products The EU classifies Methionyl rh-Polypeptide-83 as "permitted". Safety rating: MODERATE.

Is Methionyl rh-Polypeptide-83 allowed in the EU?

Methionyl rh-Polypeptide-83 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methionyl rh-Polypeptide-83 do in cosmetics?

Methionyl rh-Polypeptide-83 functions as: Skin Conditioning (consistent with rh-Polypeptide class entries in CosIng). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Methionyl rh-Polypeptide-83?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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