Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1

INCI: METHIONYL SH-OLIGOPEPTIDE-1 SR-JELLYFISH POLYPEPTIDE-1

CAS Number
Not assigned
Function
Skin Conditioning, Skin Protecting (inferred from component peptides - sh-Oligopeptide-1 is an EGF analog)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited commercial safety data; the sh-Oligopeptide-1 (EGF) component has been debated regarding long-term use and cell proliferation signaling; jellyfish-derived peptide component is novel with minimal independent safety assessment. Fusion of synthetic human EGF analog (sh-Oligopeptide-1) with a synthetic recombinant jellyfish polypeptide; the "sr-" prefix denotes synthetic recombinant origin; extremely rare in commercial products

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Concern Level: Moderate

Frequently Asked Questions

Is Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 safe in cosmetics?

Limited commercial safety data; the sh-Oligopeptide-1 (EGF) component has been debated regarding long-term use and cell proliferation signaling; jellyfish-derived peptide component is novel with minimal independent safety assessment. Fusion of synthetic human EGF analog (sh-Oligopeptide-1) with a synthetic recombinant jellyfish polypeptide; the "sr-" prefix denotes synthetic recombinant origin; extremely rare in commercial products The EU classifies Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 as "permitted". Safety rating: MODERATE.

Is Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 allowed in the EU?

Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 do in cosmetics?

Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1 functions as: Skin Conditioning, Skin Protecting (inferred from component peptides - sh-Oligopeptide-1 is an EGF analog). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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