Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2

INCI: METHIONYL SH-OLIGOPEPTIDE-75 SH-OLIGOPEPTIDE-2

CAS Number
Not assigned
Function
Skin Conditioning (sh-Oligopeptide-75); combined with IGF-1 analog (sh-Oligopeptide-2) properties
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited safety data specific to this fusion; theoretical concerns around IGF-1 signaling from the sh-Oligopeptide-2 component; no documented adverse effects. Combines two synthetic human peptides - sh-Oligopeptide-75 (skin conditioning) and sh-Oligopeptide-2 (IGF-1 analog) - into a single recombinant chain with methionine initiation

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Concern Level: Moderate

Frequently Asked Questions

Is Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 safe in cosmetics?

Limited safety data specific to this fusion; theoretical concerns around IGF-1 signaling from the sh-Oligopeptide-2 component; no documented adverse effects. Combines two synthetic human peptides - sh-Oligopeptide-75 (skin conditioning) and sh-Oligopeptide-2 (IGF-1 analog) - into a single recombinant chain with methionine initiation The EU classifies Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 as "permitted". Safety rating: MODERATE.

Is Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 allowed in the EU?

Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 do in cosmetics?

Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2 functions as: Skin Conditioning (sh-Oligopeptide-75); combined with IGF-1 analog (sh-Oligopeptide-2) properties. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Methionyl sh-Oligopeptide-75 sh-Oligopeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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