Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2

INCI: METHIONYL TRIPEPTIDE-46 HEXAPEPTIDE-40 DECAPEPTIDE-27 METHIONYL SH-POLYPEPTIDE-2

CAS Number
None assigned
Function
Skin conditioning (multi-functional fusion peptide combining signaling, carrier, and structural peptide domains)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Complex multi-domain recombinant fusion protein; QC is more demanding due to the larger construct (multiple functional domains increase folding and stability risks). Endotoxin, aggregation, and bioactivity verification are critical.. An exceptionally complex four-domain recombinant fusion peptide - sh-Polypeptide-2 is a recombinant TGF-ฮฒ (Transforming Growth Factor beta) analog, fused with Tripeptide-46, Hexapeptide-40, and Decapeptide-27 functional peptide segments. This architecture targets...

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Concern Level: Moderate

Frequently Asked Questions

Is Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 safe in cosmetics?

Complex multi-domain recombinant fusion protein; QC is more demanding due to the larger construct (multiple functional domains increase folding and stability risks). Endotoxin, aggregation, and bioactivity verification are critical.. An exceptionally complex four-domain recombinant fusion peptide - sh-Polypeptide-2 is a recombinant TGF-ฮฒ (Transforming Growth Factor beta) analog, fused with Tripeptide-46, Hexapeptide-40, and Decapeptide-27 functional peptide segments. This architecture targets... The EU classifies Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 as "permitted". Safety rating: MODERATE.

Is Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 allowed in the EU?

Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 do in cosmetics?

Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2 functions as: Skin conditioning (multi-functional fusion peptide combining signaling, carrier, and structural peptide domains). It is classified as a cosmetic ingredient in our database. CAS number: None assigned.

What is the Margin of Safety for Methionyl Tripeptide-46 Hexapeptide-40 Decapeptide-27 Methionyl sh-Polypeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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