Methoxy PEG-12 Eicosapentaenoate

INCI: METHOXY PEG-12 EICOSAPENTAENOATE

CAS Number
Not publicly assigned/available
Function
Anti-sebum, skin conditioning, skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PEG ethoxylation impurity risks; the EPA (eicosapentaenoic acid) component is an omega-3 fatty acid generally regarded as beneficial, though oxidative stability of the polyunsaturated chain must be managed in formulation. A PEGylated ester of EPA (omega-3 fatty acid); the PEG-12 chain enhances water dispersibility of the otherwise oil-soluble EPA moiety; anti-sebum activity is a distinguishing function not common among PEG derivatives

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-12 Eicosapentaenoate safe in cosmetics?

PEG ethoxylation impurity risks; the EPA (eicosapentaenoic acid) component is an omega-3 fatty acid generally regarded as beneficial, though oxidative stability of the polyunsaturated chain must be managed in formulation. A PEGylated ester of EPA (omega-3 fatty acid); the PEG-12 chain enhances water dispersibility of the otherwise oil-soluble EPA moiety; anti-sebum activity is a distinguishing function not common among PEG derivatives The EU classifies Methoxy PEG-12 Eicosapentaenoate as "prohibited". Safety rating: MODERATE.

Is Methoxy PEG-12 Eicosapentaenoate allowed in the EU?

Methoxy PEG-12 Eicosapentaenoate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-12 Eicosapentaenoate do in cosmetics?

Methoxy PEG-12 Eicosapentaenoate functions as: Anti-sebum, skin conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.

What is the Margin of Safety for Methoxy PEG-12 Eicosapentaenoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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