Regulatory Status
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Safety Data
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Expert Verdict
Retinoid-class concerns (photosensitivity, potential teratogenicity at high systemic doses) are significantly mitigated by the PEG conjugation and amide bond, which reduce penetration and systemic absorption. Described chemically as "retinoic acid amide, N-(methylpoly(oxyethylene)) (12 mol EO average)"; the amide linkage to PEG-12 creates a water-soluble, milder retinoid derivative that is more stable than retinol. Found in products such as The Face Shop Dr.Belmeur Red Pro-Retinol Serum.
Regulatory Flags
Frequently Asked Questions
Is Methoxy PEG-12 Retinamide safe in cosmetics?
Retinoid-class concerns (photosensitivity, potential teratogenicity at high systemic doses) are significantly mitigated by the PEG conjugation and amide bond, which reduce penetration and systemic absorption. Described chemically as "retinoic acid amide, N-(methylpoly(oxyethylene)) (12 mol EO average)"; the amide linkage to PEG-12 creates a water-soluble, milder retinoid derivative that is more stable than retinol. Found in products such as The Face Shop Dr.Belmeur Red Pro-Retinol Serum. The EU classifies Methoxy PEG-12 Retinamide as "prohibited". Safety rating: MODERATE.
Is Methoxy PEG-12 Retinamide allowed in the EU?
Methoxy PEG-12 Retinamide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Methoxy PEG-12 Retinamide do in cosmetics?
Methoxy PEG-12 Retinamide functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.
What is the Margin of Safety for Methoxy PEG-12 Retinamide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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