Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer

INCI: METHOXY PEG-125 ETHYLAMIDO HEXAPEPTIDE-72 SODIUM GLUTAMATE/VALINE COPOLYMER

CAS Number
Not publicly assigned/available
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Complex peptide-PEG conjugate with amino acid copolymer; PEG impurity considerations apply; peptide portion is biocompatible; the high MW limits systemic absorption. A synthetic macromolecular conjugate combining Hexapeptide-72 (a bioactive signaling peptide) with a PEG-125 backbone and a glutamate/valine amino acid copolymer segment; the PEG chain improves aqueous solubility and delivery, while the amino acid copolymer may enhance skin affinity and sustained release

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer safe in cosmetics?

Complex peptide-PEG conjugate with amino acid copolymer; PEG impurity considerations apply; peptide portion is biocompatible; the high MW limits systemic absorption. A synthetic macromolecular conjugate combining Hexapeptide-72 (a bioactive signaling peptide) with a PEG-125 backbone and a glutamate/valine amino acid copolymer segment; the PEG chain improves aqueous solubility and delivery, while the amino acid copolymer may enhance skin affinity and sustained release The EU classifies Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer as "prohibited". Safety rating: MODERATE.

Is Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer allowed in the EU?

Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer do in cosmetics?

Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.

What is the Margin of Safety for Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methoxy PEG-125 Ethylamido Hexapeptide-72 Sodium Glutamate/Valine Copolymer in your formulation.