Methoxy PEG-13 Ethyl Polysilsesquioxane

INCI: METHOXY PEG-13 ETHYL POLYSILSESQUIOXANE

CAS Number
Not publicly assigned/available
Function
Film forming, skin conditioning, texture enhancement
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - CIR has assessed polysilsesquioxane ingredients as safe in cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Polysilsesquioxane molecules are too large for dermal absorption; non-comedogenic; PEG ethoxylation impurity trace concerns apply to the PEG-13 segment. A hybrid silicone-PEG material combining the cage/ladder silsesquioxane structure (excellent film-forming, oil-absorbing, and mattifying properties) with a PEG-13 hydrophilic chain for improved water dispersibility; provides a silky, non-greasy skin feel and optical blurring effects typical of silsesquioxane powders

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-13 Ethyl Polysilsesquioxane safe in cosmetics?

Polysilsesquioxane molecules are too large for dermal absorption; non-comedogenic; PEG ethoxylation impurity trace concerns apply to the PEG-13 segment. A hybrid silicone-PEG material combining the cage/ladder silsesquioxane structure (excellent film-forming, oil-absorbing, and mattifying properties) with a PEG-13 hydrophilic chain for improved water dispersibility; provides a silky, non-greasy skin feel and optical blurring effects typical of silsesquioxane powders The EU classifies Methoxy PEG-13 Ethyl Polysilsesquioxane as "prohibited". Safety rating: MODERATE.

Is Methoxy PEG-13 Ethyl Polysilsesquioxane allowed in the EU?

Methoxy PEG-13 Ethyl Polysilsesquioxane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-13 Ethyl Polysilsesquioxane do in cosmetics?

Methoxy PEG-13 Ethyl Polysilsesquioxane functions as: Film forming, skin conditioning, texture enhancement. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.

What is the Margin of Safety for Methoxy PEG-13 Ethyl Polysilsesquioxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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