Methoxy PEG-200 Betulin

INCI: METHOXY PEG-200 BETULIN

CAS Number
Not individually assigned in public databases
Function
Skin conditioning - PEGylated derivative of betulin (a pentacyclic triterpene from birch bark) to enhance water solubility
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition; considered a cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

General PEG contamination concerns; betulin itself is well-tolerated but data on this high-molecular-weight PEGylated form is limited. Very high PEG chain (200 EO units, ~8,800 g/mol) dramatically increases water solubility of the otherwise poorly soluble betulin; betulin offers anti-inflammatory and wound-healing properties

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-200 Betulin safe in cosmetics?

General PEG contamination concerns; betulin itself is well-tolerated but data on this high-molecular-weight PEGylated form is limited. Very high PEG chain (200 EO units, ~8,800 g/mol) dramatically increases water solubility of the otherwise poorly soluble betulin; betulin offers anti-inflammatory and wound-healing properties The EU classifies Methoxy PEG-200 Betulin as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-200 Betulin allowed in the EU?

Methoxy PEG-200 Betulin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-200 Betulin do in cosmetics?

Methoxy PEG-200 Betulin functions as: Skin conditioning - PEGylated derivative of betulin (a pentacyclic triterpene from birch bark) to enhance water solubility. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned in public databases.

What is the Margin of Safety for Methoxy PEG-200 Betulin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methoxy PEG-200 Betulin in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methoxy PEG-200 Betulin in your formulation.