Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate)

INCI: METHOXY PEG-226 ETHYLAMINO POLY(LEUCINE/BENZYL GLUTAMATE)

CAS Number
Not publicly documented
Function
Likely skin conditioning and delivery vehicle - this is a PEG-polypeptide block copolymer designed for encapsulation/delivery of actives
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition; novel ingredient category

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published safety data as a novel biotech ingredient; general PEG concerns plus potential allergenicity from polypeptide component; requires careful characterization of residuals. This is a sophisticated PEG-polypeptide amphiphilic block copolymer; the poly(leucine/benzyl glutamate) segment is biodegradable and can self-assemble into nanostructures (micelles, vesicles) for active delivery; China has been among the jurisdictions evaluating approval of such novel PEG-polypeptide ingredients

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

potential-allergen peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) safe in cosmetics?

Limited published safety data as a novel biotech ingredient; general PEG concerns plus potential allergenicity from polypeptide component; requires careful characterization of residuals. This is a sophisticated PEG-polypeptide amphiphilic block copolymer; the poly(leucine/benzyl glutamate) segment is biodegradable and can self-assemble into nanostructures (micelles, vesicles) for active delivery; China has been among the jurisdictions evaluating approval of such novel PEG-polypeptide ingredients The EU classifies Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) allowed in the EU?

Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) do in cosmetics?

Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) functions as: Likely skin conditioning and delivery vehicle - this is a PEG-polypeptide block copolymer designed for encapsulation/delivery of actives. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly documented.

What is the Margin of Safety for Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methoxy PEG-226 Ethylamino Poly(Leucine/Benzyl Glutamate) in your formulation.