Methoxycinnamal

INCI: METHOXYCINNAMAL

CAS Number
Not confirmed from retrieved results - likely corresponds to 4-methoxycinnamaldehyde (p-methoxycinnamaldehyde). Verify in CosIng directly
Function
Fragrance
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - not specifically prohibited

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cinnamaldehyde derivatives are established contact allergens and may cause dose-related contact urticaria. The methoxy substitution may modulate (reduce or alter) sensitization potential, but cross-reactivity with cinnamal should be considered in safety assessments. An α,β-unsaturated aldehyde with a methoxy group on the phenyl ring. The methoxy substitution shifts the UV absorption profile and modifies the scent character compared to unsubstituted cinnamal. Related compounds like ethylhexyl ...

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Methoxycinnamal safe in cosmetics?

Cinnamaldehyde derivatives are established contact allergens and may cause dose-related contact urticaria. The methoxy substitution may modulate (reduce or alter) sensitization potential, but cross-reactivity with cinnamal should be considered in safety assessments. An α,β-unsaturated aldehyde with a methoxy group on the phenyl ring. The methoxy substitution shifts the UV absorption profile and modifies the scent character compared to unsubstituted cinnamal. Related compounds like ethylhexyl ... The EU classifies Methoxycinnamal as "permitted". Safety rating: MODERATE.

Is Methoxycinnamal allowed in the EU?

Methoxycinnamal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxycinnamal do in cosmetics?

Methoxycinnamal functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from retrieved results - likely corresponds to 4-methoxycinnamaldehyde (p-methoxycinnamaldehyde). Verify in CosIng directly.

What is the Margin of Safety for Methoxycinnamal?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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