Methoxyisopropyl Acetate

INCI: METHOXYISOPROPYL ACETATE

CAS Number
108-65-6 (primary); 84540-57-8 (secondary)
Function
Solvent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; no specific prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR Expert Panel concluded safe for use in nail care products; acetate derivative of Methoxyisopropanol - not currently in widespread cosmetic use. Also known as propylene glycol monomethyl ether acetate (PGMEA); 2-methoxy-1-methylethyl acetate

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Concern Level: Moderate

Frequently Asked Questions

Is Methoxyisopropyl Acetate safe in cosmetics?

CIR Expert Panel concluded safe for use in nail care products; acetate derivative of Methoxyisopropanol - not currently in widespread cosmetic use. Also known as propylene glycol monomethyl ether acetate (PGMEA); 2-methoxy-1-methylethyl acetate The EU classifies Methoxyisopropyl Acetate as "permitted". Safety rating: MODERATE.

Is Methoxyisopropyl Acetate allowed in the EU?

Methoxyisopropyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxyisopropyl Acetate do in cosmetics?

Methoxyisopropyl Acetate functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 108-65-6 (primary); 84540-57-8 (secondary).

What is the Margin of Safety for Methoxyisopropyl Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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