Methyl Aspartic Acid

INCI: METHYL ASPARTIC ACID

CAS Number
Likely 6384-92-5 (N-Methyl-D-aspartic acid) or related isomers
Function
Skin conditioning, Hair conditioning - amino acid derivative used to improve moisture retention
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific prohibition or restriction. Amino acid derivatives are generally well-accepted in cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low toxicity concern as an amino acid derivative. Standard considerations include pH sensitivity and formulation stability. Note that N-Methyl-D-aspartic acid is pharmacologically active as an NMDA receptor agonist at systemic doses, but dermal penetration at cosmetic use levels is negligible. Part of the natural moisturizing factor (NMF) amino acid family; enhances skin hydration through humectant activity; often used in combination with other amino acids for synergistic moisturizing effects

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Concern Level: High

Frequently Asked Questions

Is Methyl Aspartic Acid safe in cosmetics?

Low toxicity concern as an amino acid derivative. Standard considerations include pH sensitivity and formulation stability. Note that N-Methyl-D-aspartic acid is pharmacologically active as an NMDA receptor agonist at systemic doses, but dermal penetration at cosmetic use levels is negligible. Part of the natural moisturizing factor (NMF) amino acid family; enhances skin hydration through humectant activity; often used in combination with other amino acids for synergistic moisturizing effects The EU classifies Methyl Aspartic Acid as "permitted". Safety rating: MODERATE.

Is Methyl Aspartic Acid allowed in the EU?

Methyl Aspartic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Aspartic Acid do in cosmetics?

Methyl Aspartic Acid functions as: Skin conditioning, Hair conditioning - amino acid derivative used to improve moisture retention. It is classified as a cosmetic ingredient in our database. CAS number: Likely 6384-92-5 (N-Methyl-D-aspartic acid) or related isomers.

What is the Margin of Safety for Methyl Aspartic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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