Is Methyl Benzodioxepinone safe in cosmetics?
Methyl Benzodioxepinone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Benzodioxepinone
Also known as: Calone, Watermelon Ketone, 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one, 2H-1,5-Benzodioxepin-3(4H)-one, 7-methyl-, EINECS 249-320-4 (+2 more)
INCI: METHYL BENZODIOXEPINONE
Methyl Benzodioxepinone (CAS 28940-11-6) is a cosmetic cosmetic ingredient functioning as Masking, perfuming (fragrance). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 28940-11-6 →
Auto-generated CPSR Part A draft with source citations
Function
Masking, perfuming (fragrance)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
7-methyl-1,5-benzodioxepin-3-one
InChIKey
SWUIQEBPZIHZQS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - no prohibition or restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Benzodioxepinone.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Benzodioxepinone.
Regulatory Flags
potential-allergen
fragrance-component
epa_safer_alternative
ifra_fragrance
Known Synonyms
Calone
Watermelon Ketone
7-Methyl-2H-1,5-benzodioxepin-3(4H)-one
2H-1,5-Benzodioxepin-3(4H)-one, 7-methyl-
EINECS 249-320-4
7-Methyl-3,4-dihydro-2H-1,5-benzodioxepin-3-one
UNII-0NQ136C313
Chemical Function
Deodorizer
Fragrance
Regulatory Lists
IFRA Transparency
SCIL (9/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187905
Frequently Asked Questions
Is Methyl Benzodioxepinone allowed in the EU?
Methyl Benzodioxepinone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Benzodioxepinone do in cosmetics?
Methyl Benzodioxepinone functions as: Masking, perfuming (fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 28940-11-6.
Is Methyl Benzodioxepinone used outside cosmetics?
Methyl Benzodioxepinone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methyl Benzodioxepinone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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